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A Special Symposium to honor
Titia de Lange
 
Celebrating 25 Years of
the Laboratory of Cell Biology and Genetics
at The Rockefeller University


Friday, November 6, 2015
Celebratory Symposium
9:00 – 9:05 a.m.(5 minutes) Welcome Remarks Marc Tessier-Lavigne, Ph.D. President and Carson Family Professor, Laboratory of Brain Development and Repair, The Rockefeller University Caspary Auditorium
9:05 – 9:15 a.m.(10 minutes) Introductory Remarks Agata Smogorzewska, M.D., Ph.D. (MODERATOR) Associate Professor, Laboratory of Genome Maintenance, The Rockefeller University
9:15 – 9:40 a.m.(20 minutes + 5 minutes Q&A) Trypanosomes, Telomeres and Titia (and a little base J) Piet Borst, M.D., Ph.D. Professor and Group Leader, Division of Molecular Oncology, Netherlands Cancer Institute
9:40 – 10:05 a.m.(20 minutes + 5 minutes Q&A) Of Gels, Microbes and Innate Immunity Richard Flavell, Ph.D., F.R.S. Investigator, Howard Hughes Medical Institute; Sterling Professor of Immunobiology and Department Chair, Immunobiology, Yale School of Medicine
10:05 – 10:30 a.m.(20 minutes + 5 minutes Q&A) Immune Magic and the Microbiome Dan Littman, M.D., Ph.D. Helen L. and Martin S. Kimmel Professor of Molecular Immunology, Department of Pathology, and Professor, Department of Microbiology, Skirball Institute at NYU School of Medicine
10:30 – 11:00 a.m.(30 minutes) Break Abby Aldrich Rockefeller Lounge
11:00 – 11:25 a.m.(20 minutes + 5 minutes Q&A) “Oh, no, not MYC again” Laura Johnston, Ph.D. Associate Professor, Genetics and Development, Columbia University Medical Center
11:25 – 11:50 a.m.(20 minutes + 5 minutes Q&A) Synthetic Lethal Drug Combinations for the Treatment of Cancer René Bernards, Ph.D. Professor of Molecular Carcinogenesis, Utrecht University Caspary Auditorium
11:50 a.m. – 12:15 p.m.(20 minutes + 5 minutes Q&A) Remote Control of Hypothalamic Neurons Regulates Blood Glucose and Feeding Jeffrey M. Friedman, M.D., Ph.D. Marilyn M. Simpson Professor, Laboratory of Molecular Genetics, The Rockefeller University
12:15 – 1:55 p.m.(100 minutes) Lunch Break There are three dining facilities available on Rockefeller’s campus – Abby Aldrich Rockefeller Dining Room, CRC Café, and Weiss Cafeteria (click here to view a campus map – see #2, #7C, #25)
1:55 – 2:20 p.m.(20 minutes + 5 minutes Q&A) Engineering the Cancer Genome Tyler Jacks, Ph.D. Investigator, Howard Hughes Medical Institute; David H. Koch Professor of Biology and Director of the Koch Institute for Integrative Cancer Research, Massachusetts Institute of TechnologyCaspary Auditorium
2:20 – 2:45 p.m.(20 minutes + 5 minutes Q&A) Signaling DNA Damage John H.J. Petrini, Ph.D. Member, Molecular Biology Program, Sloan Kettering Institute
2:45 – 3:10 p.m.(20 minutes + 5 minutes Q&A) When Telomeres Go Bad Stephen Elledge, Ph.D. Gregor Mendel Professor, Department of Genetics, Harvard Medical School
3:10 – 3:55 p.m.(45 minutes) Coffee Break Abby Aldrich Rockefeller Lounge
3:55 – 4:20 p.m.(20 minutes + 5 minutes Q&A) It Was the Best of Times (A Tale of Two Sites) James Haber, Ph.D. Professor of Biology, and Director of the Rosenstiel Basic Medical Sciences Research Center, Brandeis University
4:20– 4:45 p.m.(20 minutes + 5 minutes Q&A) Learning from Post-Docs: New Lessons in Cancer Biology Harold Varmus, M.D. Lewis Thomas University Professor, Weill-Cornell Medical College
4:45 – 5:00 p.m.(15 minutes) Closing Remarks Titia de Lange, Ph.D. Leon Hess Professor, Laboratory of Cell Biology and Genetics, The Rockefeller University
Saturday, November 7, 2015
Symposium Day 2
9:30 – 10:30 a.m.(60 minutes) Meet & Greet and Continental Breakfast Lower Level Atrium, Collaborative Research Center (CRC)
  Session I: Chaired by Titia de Lange Carson Family Auditorium (CRC)
10:30 – 10:55 a.m.(20 minutes + 5 minutes Q&A) Repair During DNA Replication Agata Smogorzewska, M.D., Ph.D., Class of 2002 Associate Professor, Laboratory of Genome Maintenance, The Rockefeller University
10:55 – 11:20 a.m.(20 minutes + 5 minutes Q&A) A Protein Kinase C phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome Rich Wang, M.D., Ph.D., Class of 2005 Assistant Professor, Dermatology, UT Southwestern Medical Center
11:20 – 11:45 a.m.(20 minutes + 5 minutes Q&A) Telomerase Function in Human Stem Cells and Cancer Dirk Hockemeyer, Ph.D., Class of 2007 Assistant Professor, Cell and Developmental Biology, University of California, Berkeley
11:45 a.m. – 12:10 p.m.(20 minutes + 5 minutes Q&A) The Roles of Long Non-coding RNAs in Tumor Suppression Nadya Dimitrova, Ph.D., Class of 2009 Postdoctoral Fellow, The Jacks Lab, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
12:10 p.m. – 12:35 p.m.(20 minutes + 5 minutes Q&A) The Role of Aneuploidy During Tumorigenesis Teresa Davoli, Ph.D., Class of 2013 Postdoctoral Fellow, Elledge Lab, Department of Genetics, Harvard Medical School
12:35 – 1:40 p.m.(65 minutes) Lunch Lower Level Atrium (CRC)
  Session II: Chaired by Agata Smogorzewska Carson Family Auditorium (CRC)
1:40 – 2:05 p.m.(20 minutes + 5 minutes Q&A) Probing Chromatin Organization and Gene Regulation Genome Wide Bas van Steensel, Ph.D. Research Group Leader, Netherlands Cancer Institute; Adjunct Professor, Erasmus University Medical Center
2:05 – 2:30 p.m.(20 minutes + 5 minutes Q&A) Mechanisms of Telomere Cohesion Susan Smith, Ph.D. Professor, Molecular Pathogenesis Program & Department of Pathology, Skirball Institute of Biomolecular Medicine, NYU School of Medicine
2:30 – 2:55 p.m.(20 minutes + 5 minutes Q&A) Telomeres and Antigenic Variation Bibo Li, Ph.D. Professor, Department of Biology, Geology, and Environmental Science, Cleveland State University
2:55 – 3:35 p.m.(40 minutes) Coffee Break Lower Level Atrium (CRC)
3:35 – 4:00 p.m.(20 minutes + 5 minutes Q&A) Cell Cycle Regulation of Repair Pathway Choice Jan Karlseder, Ph.D. Professor and Donald and Darlene Shiley Chair, Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies
4:00 – 4:25 p.m.(20 minutes + 5 minutes Q&A) The in vivo Consequences of Acute Telomere Dysfunction Eros Lazzerini Denchi, Ph.D. Associate Professor, Department of Molecular and Experimental Medicine, The Scripps Research Institute
4:25 – 4:50 p.m.(20 minutes + 5 minutes Q&A) Telomeres; Who Gives a Cap? Agnel Sfeir, Ph.D. Assistant Professor, Department of Cell Biology, Skirball Institute of Biomolecular Medicine, NYU School of Medicine

Walk-ins are welcome. For questions, please email ruevents@rockefeller.edu.

COMMITTEE TO HONOR TITIA DE LANGE, PH.D.
  • David Baltimore, Ph.D.
  • Günter Blobel, M.D., Ph.D.
  • James E. Darnell, M.D.
  • Jeffrey M. Friedman, M.D., Ph.D.
  • Isabel P. Furlaud
    and Richard M. Furlaud
  • Joseph L. Goldstein, M.D.
  • Paul Greengard, Ph.D.
  • Marlene Hess
    and James D. Zirin
  • Paul A. Marks, M.D.
  • Peter Model, Ph.D.
    and Marjorie Russel, Ph.D.
  • Paul Nurse, Ph.D.
  • Marc Tessier-Lavigne, Ph.D.
    and Mary Hynes, Ph.D.
  • Jan T. Vilcek, M.D., Ph.D.
  • Torsten N. Wiesel, M.D.
  • Deborah E. Wiley
  • Harold E. Varmus, M.D.
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